Learn how to use NARCAN® Nasal Spray
5 STEPS to respond to an opioid poisoning
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SHOUT their name and SHAKE their shoulders.
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Call 911 if unresponsive.

illustrations-step-3

Give NARCAN® Nasal Spray.
1 spray into nostril.

illustrations-step-4

Move the person on their side (recovery position). Stay with them.
Perform rescue breathing and/or chest compressions if you know how and if needed.

illustrations-step-5

Is it working?
If not, after 2-3 minutes, use a new NARCAN® Nasal Spray device to give a second dose. Alternate nostrils with each dose.

Consult the Patient Medication Information for a full list of warnings, precautions, adverse reactions, dosing guidelines, and conditions and limitations of clinical use.
Recognize an opioid overdose
Signs of opioid poisoning include:
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Trouble breathing or not breathing
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Extreme drowsiness, passing out
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Pale and clammy skin
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Slow or no heartbeat
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Unable to be woken up by touch, shaking of shoulders, or shouting
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Very small pupils, like a pinpoint
Get NARCAN® Nasal Spray

NARCAN® Nasal Spray is used to treat someone who has overdosed on opioids. It can be used by anyone to reverse the effects of the overdose until medical help arrives. Always call 911 before using NARCAN® Nasal Spray.

This product may not be right for you. Speak with your pharmacist. Always read the label and follow the directions for use.

NARCAN® Nasal Spray device NARCAN® Nasal Spray device

WHAT IS
NARCAN® NASAL SPRAY?

NARCAN® Nasal Spray is an easy-to-use nasal form of naloxone, a medication that can reverse opioid poisoning.

HOW DOES NARCAN® NASAL SPRAY WORK?

Naloxone mechanism of action. Opioids bind to opioid receptors. Naloxone displaces the opioid. Naloxone blocks the opioid receptor.
  • Naloxone and opioids both bind to the same receptor sites in the brain
    • Naloxone does not activate opioid receptors when it binds to them. This means it doesn’t cause the same type of effects as opioids, like feeling high
  • Naloxone blocks opioids from being attached to the receptors, which can reverse the effects of opioid poisoning
    • Naloxone targets opioid receptors specifically. This means it is unlikely to cause more harm if it’s given to someone who is not experiencing opioid poisoning
  • A second dose should be given after 2 to 3 minutes if the person has not woken up or their breathing has not improved
  • Opioids may stay in the body for longer than naloxone; therefore, additional doses may be needed after temporarily reversing the poisoning and before medical help arrives

HOW DO I USE NARCAN® NASAL SPRAY?

5 STEPS to respond to an opioid poisoning

image-1-1

SHOUT their name and SHAKE their shoulders.

illustrations-step-2

Call 911 if unresponsive.

illustrations-step-3

Give NARCAN® Nasal Spray.
1 spray into nostril.

illustrations-step-4

Move the person on their side (recovery position). Stay with them.
Perform rescue breathing and/or chest compressions if you know how and if needed.

illustrations-step-5

Is it working?
If not, after 2-3 minutes, use a new NARCAN® Nasal Spray device to give a second dose. Alternate nostrils with each dose.

Consult the Patient Medication Information for a full list of warnings, precautions, adverse reactions, dosing guidelines, and conditions and limitations of clinical use.

A mother and daughter at home

EMERGENT® IS THE PROUD MAKER OF NARCAN® NASAL SPRAY

For over 25 years, we’ve been at work preparing those entrusted with protecting public health. We deliver protective solutions for health emergencies like smallpox, mpox, botulism, Ebola, anthrax, and opioid poisoning. We help prepare communities for today’s health challenges and tomorrow’s concerns by:

  • Empowering the public with the resources to respond to an opioid overdose emergency
  • Delivering medical countermeasures to fight critical, even deadly, biological events
  • Stepping up to help address emerging and infectious diseases
Learn more about Emergent

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